- Beauty, health and wellbeing
Development of pharmaceutical active ingredients
Obtaining innovative ingredients in response to production safety requirements
Research and innovation for more effective and sustainable health
At AINIA, we constantly seek innovative solutions for obtaining ingredients and active ingredients that enable our collaborating companies to be more competitive in the market. We prioritise alternative compounds obtained through sustainable, safe processes, with proven evidence of their biological effect.
In line with our commitment to responsible innovation, we use alternative techniques to animal experimentation, which enables us to verify the efficacy of compounds while ensuring the development of the expected effect, faster and at lower cost.
At AINIA, we add value
- Obtaining active pharmaceutical ingredients (APIs) through Supercritical Fluid Extraction, a clean process that enables high concentrations of active ingredient to be extracted and purified in a single stage, without leaving residues or generating polluting by-products.
- Design of biofactories for the industrial production of functional molecules and active ingredients. We start from our own collection of more than 400 natural microbial strains, selected for their specific functionalities.
- Microencapsulation of APIs, designing systems that ensure their protection and controlled release, maximising their effectiveness in the body.
- Preclinical evaluation of bioaccessibility, bioavailability and biological effect using advanced in vitro models:
- More relevant data than standardised methods
- More relevant data than standardised methods.
- Candidate screening with greater safety and lower cost.
- Mechanism of action studies in specific cellular models.
- Candidate screening with greater safety and lower cost
- Mechanism of action studies in specific cellular models
Development of pharmaceutical active ingredients
Development of pharmaceutical active ingredients using supercritical fluids: we extract, in a single extraction and purification stage, high concentrations of the active ingredient with high purity. These processes are clean, leave no type of residue or contaminant, and therefore do not require the management of discharges or by-products.
On the other hand, we design biosynthesis processes that begin with the selection of microorganisms for the industrial production of active ingredients with functional activity. Biofactories are also used to obtain molecules such as pharmaceutical active ingredients. We have our own collection of more than 400 natural strains with various functionalities.
We design microencapsulation processes to ensure the protection and controlled release of the principles that develop the biological activity for which they have been considered.
We have an integral in vitro model capable of studying the release and absorption of active ingredients for their formulation in pharmaceutical products, which enables more biorelevant preclinical data to be obtained than standardised analysis methods.
Integral platform for formulation and efficacy
- Dynamic simulation of intestinal absorption, through organ-on-chip (Ooc) technology platforms, which faithfully reproduce intestinal physiology on a chip using epithelial cell models.
- In-house gastrointestinal simulators, capable of reproducing oral, gastric and intestinal digestion and colonic fermentation to evaluate the resistance and release of bioactive compounds. Also applicable in pharmaceutical dissolution studies.
- Advanced cellular models such as bioprinting, organoids or Ooc, which enable mechanisms of action to be studied and more robust and predictive functional evidence to be obtained.
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