{"id":54694,"date":"2023-09-01T00:00:00","date_gmt":"2023-09-01T00:00:00","guid":{"rendered":"https:\/\/ainia.endesarrollo.pro\/transparencia\/healthytooth-ii\/"},"modified":"2023-09-01T00:00:00","modified_gmt":"2023-09-01T00:00:00","slug":"healthytooth-ii","status":"publish","type":"transparencia","link":"https:\/\/ainia.endesarrollo.pro\/en\/transparencia\/healthytooth-ii\/","title":{"rendered":"HEALTHYTOOTH II"},"content":{"rendered":"

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Objective<\/h2>\n

The overall objective of the project is to complete the development of a targeted antimicrobial strategy against pathogens that cause dental caries, specifically Streptococcus mutans, through the use of an endolysin.<\/p>\n

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Activities<\/h2>\n
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  1. Development and optimisation of the production process for an endolysin with lytic activity against an oral pathogen.<\/li>\n
  2. Stabilisation of an endolysin with lytic activity against oral pathogens.<\/li>\n
  3. Development and optimisation of the purification process for an endolysin with lytic activity against an oral pathogen.<\/li>\n
  4. Preclinical efficacy and safety trials of an endolysin with lytic activity against oral pathogens, using complex microbiota models and an artificial mouth system.<\/li>\n
  5. Formulation of prototypes and assessment of the stability and effectiveness of the ingredient in cosmetic matrices.<\/li>\n
  6. Analysis, evaluation and transfer of results<\/li>\n
  7. Communication and dissemination<\/li>\n<\/ol>\n

     <\/p>\n

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    Dissemination\/Transfer<\/h2>\n