{"id":57580,"date":"2026-03-09T13:39:16","date_gmt":"2026-03-09T13:39:16","guid":{"rendered":"https:\/\/ainia.endesarrollo.pro\/nutrigenomics-what-it-is-and-how-snp-nucleotides-define-the-nutrigenetic-profile-2-3\/"},"modified":"2026-05-26T12:17:26","modified_gmt":"2026-05-26T12:17:26","slug":"nutrigenomics-what-it-is-and-how-snp-nucleotides-define-the-nutrigenetic-profile-2-3","status":"publish","type":"post","link":"https:\/\/ainia.endesarrollo.pro\/en\/uncategorized\/nutrigenomics-what-it-is-and-how-snp-nucleotides-define-the-nutrigenetic-profile-2-3\/","title":{"rendered":"Nutrigenomics: What It Is and How SNP Nucleotides Define the Nutrigenetic Profile"},"content":{"rendered":"\nHow can genetic data be integrated into dietetic practice? In this article, we explain <strong>what nutrigenomics is<\/strong> and show how <strong>nucleotides<\/strong> make it possible to define a solid nutrigenetic profile. Based on that foundation, we outline an approach to translating genetic information into personalised recommendations aligned with the principles of <a href=\"https:\/\/www.ainia.com\/linea-idi\/nutricion-precision\/\"><strong>precision nutrition.<\/strong><\/a>\n\n<article><!-- INDEX --><nav aria-label=\"Index\"><strong>Index<\/strong>\n<ul>\n \t<li><a href=\"#nutrigenomica-que-es\">Nutrigenomics: what it is<\/a><\/li>\n \t<li><a href=\"#diferencias-nutrigenomica-nutrigenetica\">Differences between nutrigenomics and nutrigenetics<\/a><\/li>\n \t<li><a href=\"#test-de-nutrigenomica\">Nutrigenomics test<\/a><\/li>\n \t<li><a href=\"#snp-nucleotide-perfil-nutrigenetico\">SNP nucleotide: How to establish a nutrigenetic profile<\/a><\/li>\n \t<li><a href=\"#importancia-nutricion-precision\">Importance in precision nutrition<\/a><\/li>\n<\/ul>\n<\/nav><!-- CONTENT -->\n\n<section id=\"nutrigenomica-que-es\">\n<h2>Nutrigenomics: what it is<\/h2>\n<strong>Nutrigenomics<\/strong> studies how nutrients and bioactive compounds modulate <strong>gene expression<\/strong> and metabolic pathways. Its aim is to translate this diet-gene interaction into <strong>personalised and measurable dietary recommendations<\/strong>.\n\n<\/section><section id=\"diferencias-nutrigenomica-nutrigenetica\">\n<h3>Differences between nutrigenomics and nutrigenetics<\/h3>\n<ul>\n \t<li><strong>Nutrigenomics:<\/strong> how diet influences gene expression and biological pathways.<\/li>\n \t<li><strong>Nutrigenetics:<\/strong> how <strong>genetic variants<\/strong> (e.g., <strong>SNP nucleotide<\/strong>) condition the individual response to nutrients.<\/li>\n<\/ul>\nBoth disciplines are complementary: nutrigenetics identifies <strong>susceptibility<\/strong> (which variants a person has), and nutrigenomics helps <strong>modulate<\/strong> the response through dietary and lifestyle changes.\n\n<strong>Both are complementary<\/strong>: nutrigenetics profiles susceptibility, and nutrigenomics proposes dietary (and lifestyle) modulations to optimise the response. Recent studies insist on considering polygenicity, effect size and gene-diet-environment interactions.\n\n<\/section><section id=\"test-de-nutrigenomica\">\n<h3>Nutrigenomics test<\/h3>\nA rigorous approach usually includes:\n<ol>\n \t<li><strong>SNP nucleotide panel<\/strong> supported by scientific evidence (folate\/B12 methylation, vitamin D metabolism, lipids, caffeine\/lactose, inflammation, antioxidants, detoxification).<\/li>\n \t<li><strong>Phenotypic matrix<\/strong>: analytical parameters, habits and objective (weight, performance, cardiometabolic risk).<\/li>\n \t<li><strong>Evidence-based interpretation<\/strong>: effect size, quality\/replication of studies, possible <strong>interaction with microbiota and lifestyle<\/strong>, and <strong>degree of recommendation<\/strong>. Reviews highlight that, despite the volume of associations, <strong>clinical translation<\/strong> requires caution, independent validation and monitoring of clinical <strong>endpoints<\/strong>.<\/li>\n<\/ol>\n<table>\n<thead>\n<tr>\n<th>Component<\/th>\n<th>What it includes<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>SNP nucleotide panel<\/td>\n<td>folate\/B12 methylation, vitamin D metabolism, lipids, caffeine\/lactose, inflammation, antioxidants, detoxification<\/td>\n<\/tr>\n<tr>\n<td>Phenotypic matrix<\/td>\n<td>analytical parameters, habits and objective (weight, performance, cardiometabolic risk)<\/td>\n<\/tr>\n<tr>\n<td>Evidence-based interpretation<\/td>\n<td>effect size, quality\/replication of studies, possible interaction with microbiota and lifestyle, and degree of recommendation; caution, independent validation and monitoring of clinical endpoints<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section><section id=\"snp-nucleotide-perfil-nutrigenetico\">\n<h2>SNP nucleotide: How to establish a nutrigenetic profile<\/h2>\n<ol>\n \t<li><strong>Panel selection<\/strong>: prioritise SNPs with <strong>clinical utility<\/strong> and replicated evidence in the target of interest (e.g., lipids, blood pressure, vitamin metabolism).<\/li>\n \t<li><strong>Sampling and genotyping<\/strong>: saliva\/blood, quality control and coverage; document technical limitations.<\/li>\n \t<li><strong>Multi-source integration<\/strong>: combine genotype with <strong>biomarkers<\/strong> (e.g., 25(OH)D, lipid profile), dietary records and lifestyle factors; where appropriate, consider <strong>microbiota\/metabolomics<\/strong>.<\/li>\n \t<li><strong>Practical translation<\/strong>: adjust macros (quality of fats and carbohydrates), <strong>micronutrients<\/strong> (active forms and doses), bioactives (e.g., polyphenols, caffeine according to metabolism) and <strong>behaviours<\/strong> (sleep, activity) that modulate pathways affected by SNPs.<\/li>\n \t<li><strong>Follow-up and reassessment<\/strong>: define indicators (biomarkers and clinical outcomes) and review the plan in the event of changes in objective or new evidence.<\/li>\n<\/ol>\n<\/section><section id=\"importancia-nutricion-precision\">\n<h2>Importance in precision nutrition<\/h2>\n<strong>Precision nutrition<\/strong> seeks to define <strong>personalised dietary strategies<\/strong> to correct metabolic imbalances <strong>and improve quality of life<\/strong>, integrating knowledge of the <strong>intestinal microbiome<\/strong>, the functioning of the <strong>microbiota<\/strong> and the <strong>genetic information<\/strong> of each person. This approach makes it possible to understand with greater granularity how diet impacts the body and to design guidelines tailored to the individual, rather than average recommendations.\n\nThe integration of <strong>nutrigenomics and SNPs<\/strong> makes it possible to move from general recommendations to <a href=\"https:\/\/www.ainia.com\/linea-idi\/nutricion-precision\/\"><strong>targeted and measurable interventions<\/strong><\/a>. These are some of the benefits:\n<ul>\n \t<li><strong>Greater clinical response<\/strong>: prioritisation of targets (methylation, inflammation, lipids) with fine-tuned adjustments.<\/li>\n \t<li><strong>Personalised prevention<\/strong>: early detection of susceptibilities and protective dietary modifications.<\/li>\n \t<li><strong>Clear risk communication<\/strong>: reports with understandable language, limits and realistic expectations<\/li>\n<\/ul>\nIn practice, precision nutrition integrates <strong>multiple dimensions<\/strong> <strong>of the individual<\/strong> (lifestyle, genetics, microbiota, metabolic response) to select targets and measure outcomes objectively, which strengthens <strong>clinical translation<\/strong> and adherence to the guideline.\n\n<img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-188344 size-large\" src=\"https:\/\/ainia.endesarrollo.pro\/wp-content\/uploads\/nutrigenomica-2-1-1-1024x683-1.jpg\" alt=\"scientists in the laboratory (nutrigenomics)\" width=\"1024\" height=\"683\" \/>\n\n<\/section><\/article>\n","protected":false},"excerpt":{"rendered":"<p>How can genetic data be integrated into dietetic practice? In this article, we explain what nutrigenomics is and show how nucleotides make it possible to define a solid nutrigenetic profile. Based on that foundation, we outline an approach to translating genetic information into personalised recommendations aligned with the principles of precision nutrition. Index Nutrigenomics: what [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":50900,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[230],"tags":[],"tipo-documento":[],"class_list":["post-57580","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nutrigenomics: How SNPs Define the Nutrigenetic Profile - AINIA<\/title>\n<meta name=\"description\" content=\"Discover what nutrigenomics is, how SNPs help define a nutrigenetic profile, and why this approach is key to delivering personalised precision nutrition strategies.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta 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